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Pandemics & outbreaks: the mental health side

An outbreak touches far more than our bodies. Whatever you carried through it, your feelings make sense, and most people find their way back.

⏱ 6 min read📑 11 sections📚 31 sources✅ Reviewed October 2026

By the numbers

What research tells us about COVID-19 and mental health.

World

25%rise in how common anxiety and depression were worldwide in the first year of the COVID-19 pandemic (WHO, 2022).
76 millionextra cases of anxiety disorders and 53 million extra cases of major depression worldwide in 2020, by one large estimate.
1.5 million+children around the world lost a parent, grandparent or other caregiver to COVID-19 in its first 14 months (estimate).
23%of healthcare workers in early studies reported anxiety, and about 23% reported depression; nearly 39% had trouble sleeping (2020).

United States

9close relatives (grandparent, parent, sibling, spouse or child) are left grieving, on average, for each American who dies of COVID-19.
67%of U.S. adults said they were sleeping more or less than they wanted one year into the pandemic (2021).
47%of U.S. adults said they had delayed or canceled health care since the pandemic began (2021).
31%of Asian American adults said they had faced slurs or jokes about their race since the outbreak began (2020).

Young people

37%of U.S. high school students said their mental health was poor most of the time or always during the pandemic (2021).
44%of U.S. high school students felt sad or hopeless almost every day for two weeks or more in the past year (2021).
28% vs 45%Poor mental health was much less common among teens who felt close to people at school than among those who didn’t.
46%of Gen Z adults said their mental health was worse than before the pandemic, more than any other age group (2021).

How outbreaks affect the mind

Why a disease outbreak weighs on mental health, even for people who never get sick.

A pandemic is a disease outbreak that spreads across many countries. The World Health Organization declared COVID-19 a pandemic on March 11, 2020. In May 2023, WHO said it was no longer a global health emergency, but an ongoing health issue.

WHO names many reasons mental health suffered: isolation, loneliness, fear of infection, illness and death of loved ones, grief, and money worries. Exhausted health workers were hit hard too.

Researchers who study pandemic stress found that worry tends to cluster into a few common forms. Many people feel more than one.

🧼 Danger and germ fearsFear of catching the illness, or of touching things that might carry it.
Read more

Fear of infection and of possibly contaminated surfaces was one of the most common pandemic worries researchers measured.

Some caution is healthy and protective. It becomes heavy when it takes over your day or keeps growing even when the risk is low.

If germ fears feel stuck or need lots of rituals to calm, the “Contamination OCD” guide in this app explains what can help.
💸 Money and job worriesFear of losing work, income or housing as the economy shifts.
Read more

Fears about the economic effects of a pandemic formed their own cluster of stress in research.

SAMHSA lists time off work, lost income and job security, and trouble getting groceries and basics among the most common worries during an outbreak.

The “Money stress & your mind” and “Job loss & job hunting” guides go deeper on this kind of stress.
🔁 Checking and reassuranceChecking news, symptoms or case counts over and over to feel safer.
Read more

Compulsive checking and reassurance-seeking about pandemic threats was another pattern researchers found.

Checking can calm worry for a moment, but often makes it come back stronger. SAMHSA suggests staying up to date while limiting news, since around-the-clock coverage tends to raise anxiety.

🚷 Fear of othersFear or suspicion of people seen as “carrying” the illness.
Read more

Researchers also measured fear of outsiders who might spread infection. This kind of fear can turn into unfair blame of whole groups.

The section “Stigma, blame & fear of others” in this guide looks at how that harms people and what helps.

🌩️ Traumatic stressNightmares, unwanted thoughts or images, and feeling on edge.
Read more

Some people had nightmares and intrusive thoughts about the pandemic. These traumatic stress reactions were another cluster in research.

SAMHSA advises reaching out to a clinical provider if reactions like these last 2 to 4 weeks or more.

Feeling afraid, sad or unsettled during an outbreak is a human response to a real threat. It is not a sign of weakness.

Fear of getting sick, and of making others sick

Worry for yourself, your family, and the people you might expose.

During an outbreak, worry often reaches beyond your own health. SAMHSA lists fear about the health of people you may have exposed, and fear that friends or family will resent you if they have to stay home because of you.

Feeling watched can add stress too. Monitoring yourself for symptoms, or being monitored by others, is a common source of anxiety.

👵 Worry for loved onesFear for older relatives, babies, or family members with health conditions.
Read more

Worrying about people who could get very sick is natural. It shows how much you care.

SAMHSA also names worry about caring for children or others who depend on you as a common outbreak stress.

Turn worry into a plan: who would check on them, who would bring supplies, and how you would stay in touch.
💔 Guilt about spreading itBlaming yourself if someone you were near became ill.
Read more

Infectious illness spreads in ways no one can fully control. Getting sick, or passing it on, is not a moral failing.

If guilt stays heavy, especially after a loss, the “Survivor’s guilt” guide in this app may help.

😤 Anger at othersFeeling angry if you believe someone’s carelessness exposed you.
Read more

SAMHSA lists anger about being exposed through other people’s negligence among typical reactions.

Anger is a normal signal that something felt unfair. Naming it, moving your body, or talking it through can help it pass without harming relationships.

📱 Information overloadMixed messages and rumours that make it hard to know what’s true.
Read more

Media coverage can make the danger feel closer than it is. SAMHSA suggests looking to credible sources and avoiding news 24/7.

A WHO review found misinformation in up to 28.8% of social media posts about COVID-19.

The “Finding trustworthy health information” guide shows simple ways to check a claim before it worries you.
If worry about health keeps growing even when you are safe, a clinical provider or therapist can help. You don’t have to wait for it to become unbearable.

Isolation, loneliness & lost routines

What happens when the usual ways we connect suddenly close.

Outbreaks can close schools, workplaces, gyms, places of worship and events. SAMHSA notes that social distancing is meant to slow the spread, but it can leave people feeling cut off from the world and from loved ones.

A review of 34 studies with over 215,000 people found loneliness rose during the COVID-19 pandemic compared with before. The increase was small on average, but it was real.

🫥 LonelinessMissing hugs, shared meals and easy everyday contact.
Read more

WHO names loneliness and isolation as key reasons mental health worsened during COVID-19. Isolation limited people’s ability to work, lean on loved ones and take part in community life.

The “Loneliness: understanding it” guide has more on why loneliness hurts and how connection can be rebuilt.
🥱 Boredom and frustrationDays that blur together when you can’t work or do your usual things.
Read more

A major review of quarantine research found boredom and frustration were common stressors, along with longer time apart.

SAMHSA lists boredom and frustration about not being able to work or do daily activities among typical reactions.

🎓 Lost milestonesGraduations, weddings, birthdays and goodbyes that were canceled or changed.
Read more

The National Child Traumatic Stress Network notes that outbreaks can disrupt routines and important life events for families.

Missing these moments is a real loss. It’s okay to grieve them, even if others had it harder.

🌙 Sleep and daily rhythmSleeping too much, too little, or at odd hours.
Read more

One year into the COVID-19 pandemic, 2 in 3 U.S. adults said they were sleeping more or less than they wanted.

The “Sleep & mental health” and “Morning & evening routines” guides have ideas for steadying your days.
For practical ways to get through time stuck at home, see the sibling guide “Getting through quarantine & isolation at home.”

Grief when goodbyes couldn’t happen

Losing people, and losing the usual ways to mourn them.

Pandemics bring loss on a huge scale. Researchers estimate that each COVID-19 death in the U.S. leaves about nine close relatives grieving.

A review of 28 studies found that bereaved families faced extra pain: not being present in final moments, being left out of care, changed funerals, and weaker support from their communities. It also found many signs of resilience and coping.

🚪 Not being there at the endVisiting limits that kept families apart in someone’s final days.
Read more

Being absent during a loved one’s final moments was one of the hardest parts of pandemic loss for many families.

If you couldn’t be there, it was not because you didn’t love them. Writing a letter, recording a message, or sharing memories can help say what was left unsaid.

⚱️ Changed funerals and ritualsSmall, delayed or online services instead of the gatherings people needed.
Read more

A review of research on funerals found the benefit of rituals depends on whether people can shape them and say goodbye in a way that feels meaningful to them.

That means it’s never too late. Some families hold a memorial, plant a tree, or mark an anniversary once it feels right.

🧸 Children who lost caregiversOver a million children lost a parent or caregiver to COVID-19.
Read more

From March 2020 to April 2021, an estimated 1.1 million children worldwide lost a parent or custodial grandparent, and over 1.5 million lost a primary or secondary caregiver.

The researchers call this a “hidden pandemic” and say psychosocial and economic support can help families care for these children.

⏳ Grief that lingersWhen mourning stays very intense for a long time.
Read more

In one Dutch study, grief levels a year or more after a COVID-19 loss were similar to grief after other natural deaths. Sudden, unnatural losses tended to bring heavier early grief.

If grief still feels as raw as day one many months later, the “Prolonged & complicated grief” guide explains what can help.
Collective loss can feel lonely when everyone is grieving at once. Your grief still deserves room and care. See “Grief: understanding loss” for gentle ways to cope.

Frontline and essential workers

The strain on people who kept caring, cleaning, stocking and delivering.

Healthcare workers stood at the front of the pandemic. WHO says exhaustion among health workers was a major trigger for serious distress.

A 2020 review of 13 studies with over 33,000 healthcare workers found about 23% reported anxiety, about 23% reported depression, and nearly 39% had trouble sleeping. Nurses and women reported higher rates.

🏥 Healthcare workersLong shifts, fear of bringing illness home, and so much loss.
Read more

Early research found many healthcare workers struggled with mood and sleep during the outbreak, and called for ways to protect their mental health.

The “Nurses’ mental health”, “Doctors’ mental health” and “Moral injury in healthcare” guides go deeper on this.
🛒 Essential workersGrocery, transit, delivery, cleaning, care and factory workers who kept going.
Read more

In 2021, U.S. essential workers were more than twice as likely as other workers to have received mental health care since the pandemic began (34% vs 12%).

Their work kept communities running, often with more exposure and less choice. Their stress deserves recognition too.

👪 Parents and caregiversWorking, teaching and caring all at once.
Read more

Nearly half of U.S. parents (48%) said their stress had increased since before the pandemic. Among parents whose children were still learning from home, it was 62%.

The “Parents’ mental health” and “Caregiver stress & burnout” guides have support for carers.
Helpers need help too. Reaching out is part of being able to keep caring for others.

Who was hit hardest

An outbreak doesn’t land on everyone the same way.

WHO found the pandemic’s mental health effects were uneven. Some groups carried far more of the weight.

🧑‍🎓 Young peopleTeens and young adults lost school, friends and milestones at a key time of life.
Read more

WHO says young people were especially affected and at higher risk of self-harm.

In 2021, 37% of U.S. high school students said their mental health was poor most of the time or always during the pandemic.

👩 WomenWomen reported more distress than men across many studies.
Read more

WHO says women were more severely affected than men.

A review of 134 groups of people followed over time found small worsening of anxiety, depression and general mental health among women in particular.

🫁 People with health conditionsPeople living with asthma, cancer, heart disease and other conditions.
Read more

WHO says people with physical health conditions were more likely to develop symptoms of mental health conditions.

A review of 65 studies also found the early rise in symptoms was most pronounced among people with physical health conditions.

The “Living with chronic illness” guide has more support.
💙 People living with mental health conditionsDisrupted care at a time when it was needed most.
Read more

WHO reports that mental health services were among the most disrupted of all essential health services during much of the pandemic.

WHO also notes people with existing mental health conditions, especially severe ones, were more likely to become very ill if infected.

🏚️ People not safe at homeStay-at-home orders could trap people with someone who hurts them.
Read more

A review of 18 studies found reported domestic violence rose after stay-at-home and lockdown orders.

National Domestic Violence Hotline: call 1-800-799-7233 or text START to 88788, free and open 24/7. If you are in immediate danger, call 911.
🕊️ Families who lost someoneGrief on top of everything else.
Read more

WHO lists the illness and death of loved ones, and grief after bereavement, among the main causes of worse mental health during COVID-19.

The section “Grief when goodbyes couldn’t happen” in this guide covers this more.

Stigma, blame & fear of others

How fear can turn into unfair treatment, and how to push back.

WHO warns that outbreaks can bring social stigma. People may be labelled, stereotyped or treated differently because of a perceived link to the disease.

Stigma can land on people who were sick, their families and caregivers, and on people who simply share a background with a group that gets blamed.

🚫 Blaming whole groupsWhen a community or ethnicity is unfairly linked to an illness.
Read more

WHO notes COVID-19 led to discrimination against people of certain ethnic backgrounds.

In a 2020 survey, 31% of Asian American adults said they had faced slurs or jokes about their race since the outbreak, and 26% said they had feared being threatened or attacked.

🛏️ People who were sickFriends and neighbours staying away even after someone has recovered.
Read more

SAMHSA notes that people who were isolated because of illness may feel sad or angry when others still fear catching it from them, even after they are no longer contagious.

SAMHSA says learning and sharing accurate information about the real risk often calms these fears and helps people reconnect.

🧑‍⚕️ Health workersBeing avoided because of where you work.
Read more

WHO says stigma can reach anyone seen as having been in contact with the virus.

People who care for the sick deserve support, not suspicion.

Small ways to push back on stigma

  • Check in on neighbours who were sick or are recovering
  • Gently correct rumours with facts from trusted health sources
  • Say “people who have the illness” rather than using labels
  • Speak up, or report it, when you see harassment, if it is safe to do so
  • Talk about an illness by its proper name, not a place or group
Viruses don’t choose people by background. Fear is understandable; blame is not fair to anyone.

What research after COVID-19 found

A real rise in distress, and a lot of quiet resilience.

Large modelling studies found a real rise in anxiety and depression worldwide in 2020. Places hit hardest by infections and by restrictions on movement saw the biggest increases.

Studies that followed the same people over time tell a more hopeful story. A review of 65 such studies found a small rise in symptoms in March–April 2020 that faded to near pre-pandemic levels by mid-2020 for most groups.

🌱 Most people adaptedFor the general public, average changes were small.
Read more

A 2023 review of 134 groups followed before and during the pandemic found most changes in anxiety, depression and general mental health were close to zero. Depression worsened only slightly.

Averages can hide people who struggled a lot. But they also show how much resilience people have.

🌧️ Some struggles lastedLow mood rose more than anxiety and stayed higher for longer.
Read more

In the review of 65 studies, increases in depression and mood symptoms tended to be larger and were still raised in May–July 2020.

Women, young people and people with health conditions were more likely to feel lasting effects.

🚧 Care was disruptedMany people couldn’t get help when they needed it.
Read more

WHO found that by the end of 2021, mental health services had improved somewhat, but many people still couldn’t get care. Many turned to online support.

In early 2021, 47% of U.S. adults said they had delayed or canceled health care.

🧠 Long COVIDSymptoms that last months or years after the illness.
Read more

The CDC describes Long COVID as a wide range of symptoms that can last months or years after infection. These can include fatigue, “brain fog”, sleep problems, depression or anxiety.

Symptoms can come and go, and often get worse after physical or mental effort.

The “Brain fog: causes and what helps” guide has more, and a clinical provider can help you find care.
🫂 Connection protected peopleFeeling close to others made a measurable difference.
Read more

Among U.S. high school students in 2021, those who felt close to people at school were far less likely to report poor mental health (28% vs 45%) or persistent sadness (35% vs 53%).

If you are still feeling the effects years later, you are not “behind.” Recovery has its own pace, and support can still help.

How community helps

Neighbours, friends and groups that help everyone get through.

SAMHSA calls reaching out to people you trust one of the best ways to ease anxiety, low mood, loneliness and boredom during an outbreak.

CDC researchers found connection, both in person and online, was linked with better mental health for teens. They suggest building connection with family, school and community during and after a pandemic.

Ways to support each other during an outbreak

  • Checking in on older or isolated neighbours by phone or at the door
  • Faith and community groups meeting online or outdoors
  • Grocery and errand runs for people who can’t go out
  • Holding memorials once it is safe to gather
  • Sharing reliable information instead of rumours
💬 Supporting someone who is strugglingSimple ways to be there for a friend or family member.
Read more
  • Ask how they are really doing, and listen without rushing to fix
  • Offer something specific, like a call each Sunday or dropping off food
  • Remember hard dates, like the anniversary of a loss
  • Share helplines gently if they seem overwhelmed
The “Psychological first aid: helping people after a crisis” guide has more on supporting people through hard times.
🙌 Helping by helpingDoing something for others can ease your own helplessness.
Read more

WHO’s guidance during COVID-19 encouraged people to support neighbours and others in their community.

Research on quarantine also found that seeing it as protecting others, rather than only as a rule, could make it easier to bear.

When and where to get help

Signs it’s time to reach out, and free places to start.

Reach out to a clinical provider or therapist if…

  • Alcohol or drugs have become a way to cope
  • Daily tasks, work or school feel impossible to keep up with
  • Fear, sadness or worry lasts 2 to 4 weeks or more
  • Grief still feels unbearable many months after a loss
  • Sleeping or eating is off most days
  • Thoughts of hurting yourself or someone else come up

The Disaster Distress Helpline supports anyone in the U.S. and its territories struggling with a disaster, including infectious disease outbreaks like COVID-19. Call or text 1-800-985-5990, free and open 24/7. Press 2 for Spanish; interpreters are available in over 100 languages.

Deaf and hard of hearing people can reach the Disaster Distress Helpline at the same number through their preferred relay service.

Not safe at home? The National Domestic Violence Hotline is free and open 24/7: call 1-800-799-7233 or text START to 88788.

Outside the U.S.? Find A Helpline (findahelpline.com) lists free, confidential helplines by country.

If you’re in crisis, call or text 988 (U.S.), or text HOME to 741741. If a life is in danger, call 911.

📝 Worksheets for this guide

Fill these in privately in the app. Your answers stay on your phone.

My pandemic storyPutting a hard time into words can help you make sense of it and notice how far you’ve come.
My outbreak worry checkSort health worries into facts and fears, then choose one calm next step.
Remembering someone I lostFor losses during an outbreak, when goodbyes and gatherings may not have been possible.
My support circleMap the people and places you can lean on, and who might need you.
🔒 Fill in privately in the Mentally United Wellness App. Free, no ads, no accounts.

Sources

  1. World Health Organization (WHO) (2022). COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide
  2. The Lancet (peer-reviewed) (2021). Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic (COVID-19 Mental Disorders Collaborators)
  3. The Lancet (peer-reviewed) (2021). Global minimum estimates of children affected by COVID-19-associated orphanhood and deaths of caregivers: a modelling study (Hillis SD, et al.)
  4. Brain, Behavior, and Immunity (peer-reviewed) (2020). Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis (Pappa S, et al.)
  5. Proceedings of the National Academy of Sciences (PNAS, peer-reviewed) (2020). Tracking the reach of COVID-19 kin loss with a bereavement multiplier applied to the United States (Verdery AM, et al.)
  6. American Psychological Association (APA) (2021). Stress in America: One Year Later, A New Wave of Pandemic Health Concerns
  7. Pew Research Center (2020). Many Black and Asian Americans say they have experienced discrimination amid the COVID-19 outbreak
  8. Centers for Disease Control and Prevention (CDC) (2022). Mental Health, Suicidality, and Connectedness Among High School Students During the COVID-19 Pandemic — Adolescent Behaviors and Experiences Survey, United States, January–June 2021 (MMWR Supplement 71(3))
  9. World Health Organization (WHO) (2023). Statement on the fifteenth meeting of the IHR (2005) Emergency Committee on the COVID-19 pandemic
  10. Journal of Anxiety Disorders (peer-reviewed) (2020). Development and initial validation of the COVID Stress Scales (Taylor S, et al.)
  11. Substance Abuse and Mental Health Services Administration (SAMHSA) (2020). Taking Care of Your Behavioral Health: Tips for Social Distancing, Quarantine, and Isolation During an Infectious Disease Outbreak
  12. Bulletin of the World Health Organization (peer-reviewed) (2022). Infodemics and health misinformation: a systematic review of reviews (Borges do Nascimento IJ, et al.)
  13. American Psychologist (peer-reviewed) (2022). Loneliness before and during the COVID-19 pandemic: a systematic review with meta-analysis (Ernst M, et al.)
  14. The Lancet (peer-reviewed) (2020). The psychological impact of quarantine and how to reduce it: rapid review of the evidence (Brooks SK, et al.)
  15. National Child Traumatic Stress Network (NCTSN) (2021). Parent/Caregiver Guide to Helping Families Cope With the Coronavirus Disease 2019 (COVID-19)
  16. OMEGA – Journal of Death and Dying (peer-reviewed) (2025). The Effect of the COVID-19 Pandemic on Grief Experiences of Bereaved Relatives: An Overview Review (van Schaik T, et al.)
  17. OMEGA – Journal of Death and Dying (peer-reviewed) (2022). How do Funeral Practices Impact Bereaved Relatives’ Mental Health, Grief and Bereavement? A Mixed Methods Review with Implications for COVID-19 (Burrell A, Selman LE)
  18. Journal of Affective Disorders Reports (peer-reviewed) (2023). DSM-5-TR prolonged grief disorder levels after natural, COVID-19, and unnatural loss during the COVID-19 pandemic (Lenferink LIM, Boelen PA)
  19. BMJ (peer-reviewed) (2023). Comparison of mental health symptoms before and during the covid-19 pandemic: evidence from a systematic review and meta-analysis of 134 cohorts (Sun Y, et al.)
  20. Journal of Affective Disorders (peer-reviewed) (2022). A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020 (Robinson E, et al.)
  21. Journal of Criminal Justice (peer-reviewed) (2021). Domestic violence during the COVID-19 pandemic: evidence from a systematic review and meta-analysis (Piquero AR, et al.)
  22. World Health Organization (WHO) (2020). A guide to preventing and addressing social stigma associated with COVID-19
  23. Centers for Disease Control and Prevention (CDC) (2026). Long COVID Signs and Symptoms
  24. Centers for Disease Control and Prevention (CDC). Managing Stress
  25. World Health Organization (WHO) (2020). Mental health and psychosocial considerations during the COVID-19 outbreak (interim guidance)
  26. Substance Abuse and Mental Health Services Administration (SAMHSA) (2025). Disaster Distress Helpline
  27. Federal Emergency Management Agency (FEMA). Disaster Distress Helpline
  28. National Domestic Violence Hotline. The National Domestic Violence Hotline
  29. Office for Victims of Crime (OVC), U.S. Department of Justice. Toll Free, Text, and Online Hotlines
  30. ThroughLine (Find A Helpline). Find A Helpline
  31. International Association for Suicide Prevention (IASP). Crisis Centres & Helplines

This guide is for education and self-care. It is not a diagnosis or a substitute for professional care. Please talk to a counselor or clinical provider about your health. Reviewed October 2026.

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